LIPO A APHERESIS
Advanced Therapy for High Cardiovascular RisK
Lipo A apheresis is a specialized, FDA-approved therapy designed to lower dangerously high levels of lipoprotein(a) [Lp(a)] and LDL cholesterol in individuals who remain at increased risk for heart disease despite optimal lifestyle and medication management. At Hawaii Heart Associates, we offer this cutting-edge treatment to help address inherited and treatment-resistant cholesterol disorders.
What is Lipoprotein(a)?
Lipoprotein(a) is a unique cholesterol particle that significantly increases the risk of atherosclerotic heart disease, stroke, and calcific aortic valve stenosis. Unlike LDL cholesterol, Lp(a) levels are largely determined by genetics and are difficult to lower through conventional therapies.
How Does Lipo A Apheresis Work?
Lipo A apheresis selectively removes excess Lp(a) and LDL cholesterol from the blood through a process similar to dialysis. Each treatment produces reductions of 65–85% in these harmful cholesterol particles. Treatments are typically performed every 1–2 weeks and are well tolerated by most patients.
Who Should Consider Lipo A Apheresis?
This therapy is reserved for patients with:
Familial hypercholesterolemia or documented genetic elevation of Lp(a)
Established cardiovascular disease (such as prior heart attack, stroke, or peripheral artery disease)
LDL cholesterol or Lp(a) levels above target despite lifestyle modifications and maximally tolerated medication
Exceptional risk for heart events due to uncontrolled cholesterol
Clinical Benefits
KEY BENEFITS:
Significantly lower Lp(a) and LDL cholesterol levels
Decrease inflammation and pro-thrombotic factors
Improve microvascular health and heart function
Reduce risk for heart attacks, strokes, and disease progression
Stabilize or regress arterial plaque in select patients.
Safety and Patient Experience
Apheresis treatments at Hawaii Heart Associates are performed by skilled, compassionate professionals in a comfortable outpatient setting. Most patients report mild, temporary side effects such as fatigue. Our team ensures close monitoring and ongoing education throughout your therapy. Sessions last approximately 2-3 hours.
Insurance Coverage
Most commercial insurance and Medicare plans provide coverage for FDA-approved indications. Our administrative team will help facilitate preauthorization and answer questions about financial planning.
Learn More
If you or a loved one may benefit from Lipo A apheresis, contact Hawaii Heart Associates for a personalized evaluation. Our experts will guide you through all steps—from initial assessment to therapy management—to help you achieve the best possible cardiovascular health